The interaction of a synthetic jet (SJ) with a streamwise vortex over a flat plate were explored using stereo particle image velocimetry (SPIV) measurements in a wind tunnel. The streamwise vortex was produced by a vortex generator (VG) having heights with respect to the laminar boundary layer thickness of 1, 2, or 3. The VG was placed upstream of a synthetic jet that was skewed and pitched at 45. Time and phase-averaged flow fields were acquired with the VG alone, SJ alone with blowing ratios of 1.0 and 0.5 and were compared to a case where both the SJ and the VG were present. The time averaged data show that the interaction between the SJ and the VG brings the streamwise vortex closer to the flat plate and increases the its strength, while also increasing the streamwise velocity of the vortex core. These increases can lead to a delay in the breakdown of the streamwise vortex further downstream. An increase in the blowing ratio resulted in even more significant effects.